Robert weinberg biology of cancer ebook

The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology.

The new Second Edition has been comprehensively revised and updated to include major advances in cancer biology over the past six years. Updates include current information on:. Besides its value as a textbook, The Biology of Cancer is a useful reference for individuals working in biomedical laboratories and for clinical professionals. VetBooks February 20, Level 3 The cells will die.

The cells will continue to grow and proliferate as usual. The cells will remain viable, but will not grow and divide.

The cells will proliferate at a higher than normal rate. Which of the following is NOT true of the Src protein? Level 2 Src operates as a protein kinase. Src can serve as a kinase substrate. A and C. Elongation of the ectodomain of the receptor. Point mutations in the C-terminus of the receptor. Point mutations in the tyrosine kinase domain of the receptor. C and D. Which of the following is NOT an example of a tyrosine kinase growth factor receptor that is often altered in cancer cells?

This type of signaling loop is an example of Level 2 Endocrine signaling. Paracrine signaling. Autocrine signaling. Trans-receptor signaling. When a growth factor receptor is not bound to ligand, it is MOST likely in what configuration? Level 2 They have an extracellular ligand-binding and a transmembrane domain. Their kinase domains phosphorylate serine and threonine residues.

Which of the following statements is TRUE of the ligands of nuclear receptors? Level 2 They are hydrophobic. They may activate transcription factors. They include steroid sex hormones, retinoids, and vitamin D. Page 1. Title Page. Table of Contents. The Nature of Cancer. Tumor Viruses. Cellular Oncogenes. Growth Factors Receptors and Cancer.

Tumor Suppressor Genes. Multistep Tumorigenesis. Maintenance of Genomic Integrity and the Development of Cancer. Heterotypic Interactions and the Biology of Angiogenesis. Moving Out Invasion and Metastasis. Crowd Control Tumor Immunology and Immunotherapy.

The Rational Treatment of Cancer.